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A 24-year-old woman has a 3-year history of arthralgia and R

 
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PostPosted: Sun Jul 17, 2005 5:23 pm    Post subject: A 24-year-old woman has a 3-year history of arthralgia and R

A 24-years-old woman has a 3-year history of arthralgia and Raynaud's phenomenon. A year ago she had a miscarriage at 29 weeks, complicated by a deep vein thrombosis. Investigations show: Hb 11.2 Wcc 4.3 Platelets 145, ANA positive 1/160, DNA negative, ENA Ro positive, Anticardiolipin antibodies present at moderate titre, lupus anticoagulant present. Which statement is true?

A : She has primary antiphospholipid syndrome.
B : She should be anticoagulated for a further 6 months.
C : She has active lupus.
D : A high C reaction protein (CRP) and erythrocyte sedimentation rate (ESR) would be consistent with active lupus.
E : Hydroxychloroquine may improve her arthralgia.


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