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Which of the following is the most likely consequence of imp

 
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meenaxi
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PostPosted: Tue Nov 03, 2009 1:13 pm    Post subject: Which of the following is the most likely consequence of imp

Which of the following is the most likely consequence of impaired synthesis of IL-1?

A. enhanced phagocytic activity of circulating macrophages
B. enhanced production of antibody by B cells
C. impaired antigen processing by circulating macrophages
D. impaired function of T lymphocyte
E. impaired production of leukotrienes by neutrophils


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meenaxi
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PostPosted: Tue Nov 03, 2009 1:14 pm    Post subject:

IL - 1 is secreted by macrophages and monocytes.
It
*is endogenous pyrogen
*cytokines increase the expression of adhesion factors on endothelial cells to enable transmigration of leukocytes
*IL-1 enhances T cell-dependent antibody production through induction of CD40 ligand and OX40 on T cells.


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