The genetic disease institute at a university hospital has d

[madhurima]

The genetic disease institute at a university hospital has developed a rapid screening test for a serious but treatable inherited metabolic disorder. Although this disorder is predominantly found in a particular ethnic group, it is also found sporadically throughout the entire population. The screening test has a sensitivity of 95% and a specificity of 90%. When used in an ethnically prescreened population where the prevalence of this disorder is 30%, the positive predictive value is 80% and the negative predictive value is 96%. The institute proposes to use this screening test on the general population where the prevalence of this disease is 0.1%. Which of the following is the most likely result of this screening program?

A ) Negative predictive value decreases

B ) Positive predictive value decreases

C ) Sensitivity decreases

D ) Specificity decreases

[madhurima]

A ) Negative predictive value increase

B ) Positive predictive value decreases

C ) Sensitivity doesn't change

D ) Specificity doesn't change

b is right