Galactosemia, an inability to metabolize galactose, results

[Hijeck]

Galactosemia, an inability to metabolize galactose, results from a deficiency of the enzyme galactose-1-phosphate uridyltransferase. The table below summarizes the genotypes and phenotypes at this locus. Which of the following alleles show less than normal activity of the enzyme?

Genotype Enzyme Activity Phenotype G/G 100 Normal G/D 75 Normal G/LA 120 Normal G/g 50 Normal D/D 50 Normal D/LA 95 Normal LA/LA 140 Normal LA/g 70 Normal g/g <5 Galactosemia


A. D and G

B. D and g

C. D and LA

D. D only

E. G and g

F. G and LA

G. G only

H. g and LA

I. g only

[Hijeck]

Ans: B. D and g