[b]A 72-year-old woman comes to the physician because of increasing episodes of urinary incontinence over the past 6 months. Her incontinence usually occurs at night, she feels no sensation to urinate prior to the episodes. The episodes are less frequent if she schedules her trips to the bathroom and restricts liquid intake several hours prior to bedtime. She has a 20-year history of type 2 diabetes mellitus. Current medications include metformin and glyburide. Funduscopic examination shows mild retinopathy. Pelvic examination shows normal vaginal mucosa. Sensation to pinprick is decreased in a stocking-glove distribution. Urinalysis shows 1 + protein and no leukocyte esterase or nitrites. Which of the following is the most likely cause of this patient's urinary symptoms? [/b]
A) Functional incontinence
B) Hypersensitivity of the detrusor muscle
C) Overflow of urine from large residual volumes
D) Urethral atrophywith loss of urethrovesical angle
E) Normal aging



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