A 60-year-old man comes to the physician because of difficulty sleeping and concentrating and a 5-kg (10-lb) weight loss over the past 3 months. He also has become withdrawn. He has had chronic pain since sustaining fractures of the left lower extremity, pelvis, and several ribs in a motor vehicle collision 2 years ago. He has a previous history of alcohol abuse. He takes a nonsteroidal anti-inflammatory drug. Which of the following is the most appropriate pharmacotherapy?
A ) Carbamazepine
B ) Chlordiazepoxide
C ) Disulfiram
D ) Lithium carbonate
E ) Nortriptyline



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