All of the following statements about erythromycin are corre

All of the following statements about erythromycin are correct except

A it is mainly concentrated and excreted in an active form in the bile

B it binds irreversibly to the 50s ribosomal subunit

C it is bactericidal

D it is contraidicated in patient with hepaic dysfunction

E it is used as a penicillin substitute

C it is bactericidal