All but which of the following statements about aspirin (acetylsalicylic acid) are true?
A. Aspirin acts by irreversibly inhibiting cyclooxygenase (COX).
B. Aspirin reduces mortality in patients with unstable angina and myocardial infarction.
C. Aspirin reduces morbidity and mortality in patients who have had a stroke.
D. Aspirin is first-line therapy in elderly patients (over 65 years of age) with atrial fibrillation.
E. There is evidence for primary prevention of death and myocardial infarction in patients with risk factors for coronary artery disease.